12/19/2023 0 Comments Ambify torrent![]() Given the opportunities especially in the US, analysts have upgraded their earnings estimates and expect profits to grow 20 per cent annually over the next three years. While the Brazilian business is profitable, Nomura analysts say there is scope for improvement in profitability as Torrent’s margins at under 10 per cent are much lower than peers, who are at 20 per cent plus. Torrent, the largest Indian pharma player in Brazil, grew 14 per cent in FY15. Improvement in field force productivity should help enhance profitability of its Indian operations, which account for 35 per cent of top line. The acquisition is yet to make money at the net level. Torrent paid Rs 2,000 crore for the acquisition, completed a year ago. Going ahead, analysts expect growth to come from volume and price increase from the product portfolio of Elder Pharma. Two of the acquired brands from Elder Pharma (calcium supplement Shelcal and analgesic Chymoral Forte) are the largest selling products for Torrent.ĪLSO READ: Torrent Pharma hits record high on FIPB nod to raise FII limit The outperformance over the past three years is due to its focus on the fast-growing chronic therapy segment. Even on a trailing 12-month basis, its sales grew 21 per cent compared to 14 per cent for the industry. The risk or severity of adverse effects can be increased when Aripiprazole is combined with Acenocoumarol.In India, Torrent has been a major outperformer with April-May period sales growing 28 per cent year-on-year. The risk or severity of hypertension can be increased when Aripiprazole is combined with Acemetacin. The risk or severity of hypertension can be increased when Aripiprazole is combined with Aceclofenac. The risk or severity of hypotension can be increased when Aripiprazole is combined with Acebutolol. The therapeutic efficacy of Acarbose can be decreased when used in combination with Aripiprazole. The metabolism of Aripiprazole can be decreased when combined with Acalabrutinib. The metabolism of Aripiprazole can be decreased when combined with Abiraterone. The metabolism of Aripiprazole can be increased when combined with Abatacept. The serum concentration of Aripiprazole can be increased when it is combined with Abametapir. Found in tandem arrangement with CYP2D6*4.ġ,2-Benzodiazepine may increase the central nervous system depressant (CNS depressant) activities of Aripiprazole. Similar but not identical switch region compared to CYP2D6*68A. Poor drug metabolizer, lower dose requirement. ![]() Pathways Not Available Pharmacogenomic Effects/ADRs Hepatic and renal function as well as sex, race, and smoking status do not affect dosage requirements for aripiprazole Label, 3. Patients calssified as CYP2D6 poor metabolizers should be prescribed half the regular dose of aripiprazole Label. No dosage adjustment is necessary in elderly patients however aripiprazole is not approved for Alzheimer's associated psychosis Label. Pharmacokinetic properties in patients 10-17 years of age are similar to that of adults once body weight has been corrected for Label. Aripiprazole is present in human breast milk and so patients should either stop breastfeeding or stop taking aripiprazole depending on the risk and benefit to mother and child Label. Aripiprazole's effect on labor and delivery has not been investigated Label. These symptoms may resolve in hours or require extended hospital care Label. Neonates with third trimester exposure to aripiprazole may show extrapyramidal or withdrawal symptoms of varying severity Label. Aripiprazole should only be prescribed in pregnancy if the benefits outweigh the risks Label. In animal studies of pregnancy, aripiprazole was associated with a number of malformations and fetal death at doses higher than the maximum recommended human dose Label. In other studies of antipsychotic medication in pregnancy, children are at risk of extrapyramidal or withdrawal symptoms Label. Studies on the safety and effectiveness of aripiprazole in pregnancy have not been performed, though there is currently a national pregnancy registry for mothers currently taking aripiprazole in pregnancy Label, 6.
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